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Simcere Pharmaceutical Group recombinant human (rh) endostatin (endostar)
Recombinant Human (Rh) Endostatin (Endostar), supplied by Simcere Pharmaceutical Group, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human (rh) endostatin (endostar)/product/Simcere Pharmaceutical Group
Average 90 stars, based on 1 article reviews
recombinant human (rh) endostatin (endostar) - by Bioz Stars, 2026-02
90/100 stars

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Simcere Pharmaceutical Group recombinant human (rh) endostatin (endostar)
Recombinant Human (Rh) Endostatin (Endostar), supplied by Simcere Pharmaceutical Group, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human (rh) endostatin (endostar)/product/Simcere Pharmaceutical Group
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recombinant human (rh) endostatin (endostar) - by Bioz Stars, 2026-02
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Simcere Pharmaceutical Group human recombinant endostatin, endostar (rh-es)
Treatment schedule. Abbreviations: Ip, intraperitoneal; ES, <t>endostar;</t> GEM, gemcitabine.
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Treatment schedule. Abbreviations: Ip, intraperitoneal; ES, endostar; GEM, gemcitabine.

Journal: Cancer Management and Research

Article Title: Antitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma

doi: 10.2147/CMAR.S192868

Figure Lengend Snippet: Treatment schedule. Abbreviations: Ip, intraperitoneal; ES, endostar; GEM, gemcitabine.

Article Snippet: The human recombinant endostatin, Endostar (rh-ES), was kindly provided by Shandong Simcere Medgenn Biopharmaceutical Co. (Yantai, Shandong, China) and stored at 4 °C.

Techniques:

Tumor size, tumor weight and tumor samples of various treatment regimens. ( A ) Suppression of tumor growth after different treatment regimens in C57/BL6 mice xenografted with LLC. ( B ) Mean tumor weights of mice from different treatment regimens. ( C ) Tumor samples of mice from different treatment regimens. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: Ip, intraperitoneal; ES, endostar; GEM, gemcitabine; LLC, Lewis lung carcinoma.

Journal: Cancer Management and Research

Article Title: Antitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma

doi: 10.2147/CMAR.S192868

Figure Lengend Snippet: Tumor size, tumor weight and tumor samples of various treatment regimens. ( A ) Suppression of tumor growth after different treatment regimens in C57/BL6 mice xenografted with LLC. ( B ) Mean tumor weights of mice from different treatment regimens. ( C ) Tumor samples of mice from different treatment regimens. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: Ip, intraperitoneal; ES, endostar; GEM, gemcitabine; LLC, Lewis lung carcinoma.

Article Snippet: The human recombinant endostatin, Endostar (rh-ES), was kindly provided by Shandong Simcere Medgenn Biopharmaceutical Co. (Yantai, Shandong, China) and stored at 4 °C.

Techniques: Control

Micro 18F-FDG PET/CT imaging. ( A ) Representative 18F-FDG PET scans of mice one day after treatment with various regimens. ( B ) SUVmax associated with various treatment regimens. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: ES, endostar; GEM, gemcitabine.

Journal: Cancer Management and Research

Article Title: Antitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma

doi: 10.2147/CMAR.S192868

Figure Lengend Snippet: Micro 18F-FDG PET/CT imaging. ( A ) Representative 18F-FDG PET scans of mice one day after treatment with various regimens. ( B ) SUVmax associated with various treatment regimens. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: ES, endostar; GEM, gemcitabine.

Article Snippet: The human recombinant endostatin, Endostar (rh-ES), was kindly provided by Shandong Simcere Medgenn Biopharmaceutical Co. (Yantai, Shandong, China) and stored at 4 °C.

Techniques: Positron Emission Tomography-Computed Tomography, Imaging, Control

Cell cycle analysis of tumor tissue from mice in different groups. ( A ) Flow cytometry analysis of cell cycle redistribution in xenografts from mice in different groups. ( B ) Percentage of cells in G0/G1, S, G2/M phase in mouse xenografts in different treatment groups. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: ES, endostar; GEM, gemcitabine.

Journal: Cancer Management and Research

Article Title: Antitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma

doi: 10.2147/CMAR.S192868

Figure Lengend Snippet: Cell cycle analysis of tumor tissue from mice in different groups. ( A ) Flow cytometry analysis of cell cycle redistribution in xenografts from mice in different groups. ( B ) Percentage of cells in G0/G1, S, G2/M phase in mouse xenografts in different treatment groups. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: ES, endostar; GEM, gemcitabine.

Article Snippet: The human recombinant endostatin, Endostar (rh-ES), was kindly provided by Shandong Simcere Medgenn Biopharmaceutical Co. (Yantai, Shandong, China) and stored at 4 °C.

Techniques: Cell Cycle Assay, Flow Cytometry, Control

Expression of VEGF in Lewis tumor tissue. ( A ) Immunohistochemical staining against VEGF of xenografted Lewis treated tissues under various treatment regimens (×400 magnification). (B) VEGF positivity stain (%) within treatment groups. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: ES, endostar; GEM, gemcitabine.

Journal: Cancer Management and Research

Article Title: Antitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma

doi: 10.2147/CMAR.S192868

Figure Lengend Snippet: Expression of VEGF in Lewis tumor tissue. ( A ) Immunohistochemical staining against VEGF of xenografted Lewis treated tissues under various treatment regimens (×400 magnification). (B) VEGF positivity stain (%) within treatment groups. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: ES, endostar; GEM, gemcitabine.

Article Snippet: The human recombinant endostatin, Endostar (rh-ES), was kindly provided by Shandong Simcere Medgenn Biopharmaceutical Co. (Yantai, Shandong, China) and stored at 4 °C.

Techniques: Expressing, Immunohistochemical staining, Staining, Control

Expression of α-SMA in Lewis tumor tissue. ( A ) Immunohistochemical staining against α-SMA in xenografted Lewis treated with various treatment regimens (×200 magnification). ( B ) Number of α-SMA positive vessels within treatment groups. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: ES, endostar; GEM, gemcitabine.

Journal: Cancer Management and Research

Article Title: Antitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma

doi: 10.2147/CMAR.S192868

Figure Lengend Snippet: Expression of α-SMA in Lewis tumor tissue. ( A ) Immunohistochemical staining against α-SMA in xenografted Lewis treated with various treatment regimens (×200 magnification). ( B ) Number of α-SMA positive vessels within treatment groups. * P <0.05 vs control group, ** P <0.05 vs all groups. Abbreviations: ES, endostar; GEM, gemcitabine.

Article Snippet: The human recombinant endostatin, Endostar (rh-ES), was kindly provided by Shandong Simcere Medgenn Biopharmaceutical Co. (Yantai, Shandong, China) and stored at 4 °C.

Techniques: Expressing, Immunohistochemical staining, Staining, Control

Organs morphology of mice from different groups. Hematoxylin-eosin staining of the heart, liver, spleen, lung, kidney in different groups. ( A ) Control group, ( B ) ES alone group, ( C ) GEM alone group, ( D ) ES/GEM group, ( E ) GEM/ES group, and ( F ) ES + GEM group. Abbreviations: ES, endostar; GEM, gemcitabine.

Journal: Cancer Management and Research

Article Title: Antitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma

doi: 10.2147/CMAR.S192868

Figure Lengend Snippet: Organs morphology of mice from different groups. Hematoxylin-eosin staining of the heart, liver, spleen, lung, kidney in different groups. ( A ) Control group, ( B ) ES alone group, ( C ) GEM alone group, ( D ) ES/GEM group, ( E ) GEM/ES group, and ( F ) ES + GEM group. Abbreviations: ES, endostar; GEM, gemcitabine.

Article Snippet: The human recombinant endostatin, Endostar (rh-ES), was kindly provided by Shandong Simcere Medgenn Biopharmaceutical Co. (Yantai, Shandong, China) and stored at 4 °C.

Techniques: Staining, Control